Profesor Investigador Adolfo Virgen

Formación Académica

• Químico Farmacéutico Biólogo, Universidad de Colima
• Maestría en Ciencias Fisiológicas, Fisiología, Universidad de Colima
• Doctorado en Ciencias Fisiológicas, Fisiología, Universidad de Colima

Contacto

Centro Universitario de Investigaciones Biomédicas

Av. 25 de julio #965, Col. Villas San Sebastián, 28045-Colima, Colima, México.

e-mail:  avirgen@ucol.mx

Tel. 312 316 1129

Líneas de Investigación 

• Fisiopatología de enferemedades crónico degenerativas
• Mecanismos de regulación de alteraciones fisiológicas que ocurren durante el embarazo
• Estudio de los mecanismos involucrados en los efectos del ejercicio y ayuno intermitente en condiciones fisiológicas y no fisiológicas 
• Nanomedicina

Publicaciones

1. Rosas-Rodríguez JA, Virgen-Ortíz A, Ruiz EA, Ortiz RM, Soñanez-Organis JG. Perilipin Isoforms and PGC-1α Are Regulated Differentially in Rat Heart during Pregnancy-Induced Physiological Cardiac Hypertrophy. Medicina (Kaunas). 2022 Oct 11;58(10):1433. doi: 10.3390/medicina58101433.
2. Díaz-Reval MI, Cárdenas Y, Huerta M, Trujillo X, Sánchez-Pastor EA, González-Trujano ME, Virgen-Ortíz A, Pérez-Hernández MG. Activation of Peripheral Cannabinoid Receptors Synergizes the Effect of Systemic Ibuprofen in a Pain Model in Rat. Pharmaceuticals (Basel). 2022 Jul 23;15(8):910. doi: 10.3390/ph15080910.
3. Ceballos-Gutiérrez A, Rodríguez-Hernández A, Álvarez-Valadez MDR, Limón-Miranda S, Andrade F, Figueroa-Gutiérrez A, Díaz-Reval I, Apolinar-Iribe A, Castro-Sánchez L, Alamilla J, Sánchez-Pastor E, Virgen-Ortiz A. ZnO Nanoparticles Induce Dyslipidemia and Atherosclerotic Lesions Leading to Changes in Vascular Contractility and Cannabinoid Receptors Expression as Well as Increased Blood Pressure. Nanomaterials (Basel). 2021 Sep 7;11(9):2319. doi: 10.3390/nano11092319.
4. Aguilar-Martinez IS, Reyes-Mendez ME, Herrera-Zamora JM, Osuna-Lopez F, Virgen-Ortiz A, Mendoza-Munoz N, Gongora-Alfaro JL, Moreno-Galindo EG, Alamilla J. Synergistic antidepressant-like effect of capsaicin and citalopram reduces the side effects of citalopram on anxiety and working memory in rats. Psychopharmacology (Berl). 2020 Jul;237(7):2173-2185. doi: 10.1007/s00213-020-05528-6.
5. Virgen-Ortiz A, Apolinar-Iribe A, Díaz-Reval I, Parra-Delgado H, Limón-Miranda S, Sánchez-Pastor EA, Castro-Sánchez L, Jesús Castillo S, Dagnino-Acosta A, Bonales-Alatorre E, Rodríguez-Hernández A. Zinc Oxide Nanoparticles Induce an Adverse Effect on Blood Glucose Levels Depending On the Dose and Route of Administration in Healthy and Diabetic Rats. Nanomaterials (Basel). 2020 Oct 12;10(10):2005. doi: 10.3390/nano10102005.
6. Andrade F, Rangel-Sandoval C, Rodríguez-Hernández A, López-Dyck E, Elizalde A, Virgen-Ortiz A, Bonales-Alatorre E, Valencia-Cruz G, Sánchez-Pastor E. Capsaicin Causes Vasorelaxation of Rat Aorta through Blocking of L-type Ca2+ Channels and Activation of CB1 Receptors. Molecules. 2020 Aug 30;25(17):3957. doi: 10.3390/molecules25173957.
7. Jiménez-Maldonado A, Montero S, Lemus M, Cerna-Cortés J, Rodríguez-Hernández A, Mendoza MA, Melnikov V, Gamboa-Domínguez A, Muñiz J, Virgen-Ortiz A, Roces de Alvarez-Buylla E. Moderate and high intensity chronic exercise reduces plasma tumor necrosis factor alpha and increases the Langerhans islet area in healthy rats. J Musculoskelet Neuronal Interact. 2019 Sep 1;19(3):354-361.
8. Virgen-Ortiz A, Limón-Miranda S, Salazar-Enríquez DG, Melnikov V, Sánchez-Pastor EA, Castro-Rodríguez EM. Matrix Metalloproteinases System and Types of Fibrosis in Rat Heart during Late Pregnancy and Postpartum. Medicina (Kaunas). 2019 May 23;55(5):199. doi: 10.3390/medicina55050199.
9. Jiménez-Maldonado A, Virgen-Ortiz A, Lemus M, Castro-Rodríguez E, Cerna-Cortés J, Muñiz J, Montero S, Roces E. Effects of Moderate- and High-Intensity Chronic Exercise on the Adiponectin Levels in Slow-Twitch and Fast-Twitch Muscles in Rats. Medicina (Kaunas). 2019 Jun 19;55(6):291. doi: 10.3390/medicina55060291.